Metabolite identification studies on amiodarone in in vitro (rat liver microsomes, rat and human liver S9 fractions) and in vivo (rat feces, urine, plasma) matrices by using liquid chromatography with high-resolution mass spectrometry and multiple-stage m-Reference-Cited by-同舟云学术

Metabolite identification studies on amiodarone in in vitro (rat liver microsomes, rat and human liver S9 fractions) and in vivo (rat feces, urine, plasma) matrices by using liquid chromatography with high-resolution mass spectrometry and multiple-stage m

Published:2013-12-26 Issue:4 Volume:28 Page:311-331
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Varkhede Ninad Ramesh¹,Jhajra Shalu¹,Ahire Deepak Suresh¹,Singh Saranjit¹

Affiliation:

1. Department of Pharmaceutical Analysis; National Institute of Pharmaceutical Education and Research (NIPER); Sector 67, S.A.S. Nagar 160 062 Punjab India

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference47 articles.

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3. Identification of amiodarone metabolites in human bile by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry;Deng;Drug Metab. Dispos.,2011

4. Identification and quantitation of novel metabolites of amiodarone in plasma of treated patients;Ha;Eur. J. Pharm. Sci.,2005

5. Amiodarone N-deethylation in human liver microsomes: Involvement of cytochrome P450 3A enzymes (first report);Trivier;Life Sci.,1993

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