PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells-Reference-Cited by-同舟云学术

PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells

Published:2019-07-15 Issue:9 Volume:3 Page:1191-1204
ISSN:2471-254X
Container-title:Hepatology Communications
language:en
Short-container-title:Hepatol Commun

Author:

Bruschi Francesca Virginia¹^ORCID,Claudel Thierry¹,Tardelli Matteo¹,Starlinger Patrick²^ORCID,Marra Fabio³^ORCID,Trauner Michael¹

Affiliation:

1. Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III Medical University of Vienna Vienna Austria

2. Department of Surgery Medical University of Vienna Vienna Austria

3. Clinical Pathophysiology Department University of Florence Florence Italy

Funder

Austrian Science Fund

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep4.1395

Reference43 articles.

1. Human Fatty Liver Disease: Old Questions and New Insights

2. PNPLA3 and obesity: a synergistic relationship in NAFLD

3. Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease

4. PNPLA3 expression and its impact on the liver: current perspectives

5. PNPLA3 gene in liver diseases

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1. PNPLA3 I148 M genetic variant in autoimmune hepatitis characterises advanced disease at diagnosis and reduced survival free of cirrhotic events and liver-related mortality;Journal of Translational Autoimmunity;2024-12

2. Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models;Journal of Hepatology;2024-06

3. Unraveling the pathogenesis of non‐alcoholic fatty liver diseases through genome‐wide association studies;Journal of Gastroenterology and Hepatology;2023-08-17

4. An integrated view of anti-inflammatory and antifibrotic targets for the treatment of NASH;Journal of Hepatology;2023-08

5. PNPLA3-I148M Variant Promotes the Progression of Liver Fibrosis by Inducing Mitochondrial Dysfunction;International Journal of Molecular Sciences;2023-06-02