Using quantitative tissue phenotype to assess the margins of surgical samples from a pan-Canadian surgery study

Author:

Guillaud Martial1,MacAulay Calum E.1,Berean Kenneth W.2,Bullock Martin3,Guggisberg Kelly4,Klieb Hagen5,Puttagunta Lakshmi6,Penner Carla7,Kwan Keith8,Rosin Miriam P.2910,Poh Catherine F.1211ORCID

Affiliation:

1. Department of Integrative Oncology; BC Cancer Agency; Vancouver British Columbia Canada

2. Department of Pathology and Laboratory Medicine; the University of British Columbia; Vancouver British Columbia Canada

3. Department of Pathology; Dalhousie University; Halifax Nova Scotia Canada

4. Department of Pathology and Laboratory Medicine; University of Calgary; Calgary Alberta Canada

5. Department of Pathology; Sunnybrook Health Sciences Centre; Toronto Ontario Canada

6. Department of Laboratory Medicine and Pathology; University of Alberta; Edmonton Alberta Canada

7. Department of Pathology; University of Manitoba; Winnipeg Manitoba Canada

8. Department of Pathology and Laboratory Medicine; University of Western; London Ontario Canada

9. Department of Cancer Control Research; BC Cancer Agency; Vancouver British Columbia Canada

10. Biomedical Physiology and Kinesiology; Simon Fraser University; Burnaby British Columbia Canada

11. Faculty of Dentistry; the University of British Columbia; Vancouver British Columbia Canada

Funder

Terry Fox Research Institute

Publisher

Wiley

Subject

Otorhinolaryngology

Reference21 articles.

1. A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications;Braakhuis;Cancer Res,2003

2. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin;Slaughter;Cancer,1953

3. Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor;Leemans;Cancer,1994

4. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck;Brennan;N Engl J Med,1995

5. Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications;Tabor;Clin Cancer Res,2001

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