HS3ST2 modulates breast cancer cell invasiveness via MAP kinase- and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression

Author:

Vijaya Kumar Archana1,Salem Gassar Ezeddin12,Spillmann Dorothe3,Stock Christian4,Sen Yin-Ping5,Zhang Ting5,Van Kuppevelt Toin H.6,Hülsewig Carolin1,Koszlowski Eliene O.7,Pavao Mauro S.G.7,Ibrahim Sherif A.8,Poeter Michaela9,Rescher Ursula9,Kiesel Ludwig1,Koduru Suresh10,Yip George W.5,Götte Martin1

Affiliation:

1. Department of Gynecology and Obstetrics; Münster University Hospital; Münster Germany

2. Department of Physiology; Faculty of Medicine; Benghazi University; Libya

3. Department of Medical Biochemistry and Microbiology; The Biomedical Center, Uppsala University; Uppsala Sweden

4. Institute of Physiology II, University of Münster; Münster Germany

5. Department of Anatomy; Yong Loo Lin School of Medicine, National University of Singapore; Singapore

6. Department of Biochemistry; NCMLS; Radboud University Medical Centre; Nijmegen The Netherlands

7. Instituto de Bioquimica Medica, Universidade Federal do Rio de Janeiro; Brazil

8. Department of Zoology; Faculty of Science; Cairo University; Giza Egypt

9. Institute of Medical Biochemistry, ZMBE, University of Münster; Münster Germany

10. School of Medical Sciences, University of Hyderabad; Hyderabad India

Funder

Deutsche Forschungsgemeinschaft DFG IRTG “Molecular and Cellular GlycoSciences”

National Medical Research Council, Singapore

Deutscher Akademischer Austauschdienst DAAD Transformationspartnerschaften

DAAD PROBRAL Project

European Commission

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference50 articles.

1. Therapeutic value of glycosaminoglycans in cancer;Yip;Mol Cancer Ther,2006

2. Glycosaminoglycans: key players in cancer cell biology and treatment;Afratis;FEBS J,2012

3. Differential roles for membrane-bound and soluble syndecan-1 (CD138) in breast cancer progression;Nikolova;Carcinogenesis,2009

4. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless;Baeg;Development,2001

5. Heparan sulfate proteoglycans play a dual role in regulating fibroblast growth factor-2 mitogenic activity in human breast cancer cells;Delehedde;Exp Cell Res,1996

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