CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies

Author:

Widemann Brigitte C.1,Acosta Maria T.2,Ammoun Sylvia3,Belzberg Allan J.4,Bernards Andre5,Blakeley Jaishri4,Bretscher Antony6,Cichowski Karen7,Clapp D. Wade8,Dombi Eva1,Evans Gareth D.9,Ferner Rosalie1011,Fernandez-Valle Cristina12,Fisher Michael J.13,Giovannini Marco14,Gutmann David H.15,Hanemann C. Oliver3,Hennigan Robert16,Huson Susan9,Ingram David8,Kissil Joe17,Korf Bruce R.18,Legius Eric19,Packer Roger J.2,McClatchey Andrea I5,McCormick Frank20,North Kathryn21,Pehrsson Minja22,Plotkin Scott R.5,Ramesh Vijaya5,Ratner Nancy16,Schirmer Susann23,Sherman Larry24,Schorry Elizabeth16,Stevenson David25,Stewart Douglas R.26,Ullrich Nicole27,Bakker Annette C.28,Morrison Helen23

Affiliation:

1. Pediatric Oncology Branch; NIH-National Cancer Institute; Bethesda Maryland

2. Children's National; Gilbert NF Institute; Washington District of Columbia

3. Peninsula Schools of Medicine and Dentistry; Plymouth University; Plymouth UK

4. Johns Hopkins University; Baltimore Maryland

5. Department of Neurology and Cancer Center; Harvard Medical School; Massachusetts General Hospital; Boston Massachusetts

6. Cornell University; New York New York

7. Harvard Medical School; Brigham and Women's Hospital; Boston Massachusetts

8. Indiana University School of Medicine; Indianapolis Indiana

9. St. Mary's Hospital; University of Manchester; Manchester UK

10. Guy's and St. Thomas' NHS Foundation Trust; London UK

11. Department of Clinical Neuroscience; King's College London; London UK

12. University of Central Florida; Orlando Florida

13. Children's Hospital of Philadelphia; Philadelphia Pennsylvania

14. House Research Institute; University of Southern California; Los Angeles California

15. Washington University School of Medicine; St. Louis Missouri

16. Cincinnati Children's Hospital Medical Center; Cincinnati Ohio

17. Scripps Research Institute-Florida; Jupiter Florida

18. University of Alabama; Birmingham Alabama

19. Catholic University of Leuven; Leuven Belgium

20. University of California; San Francisco California

21. The Children's Hospital at Westmead; Westmead Australia

22. Biomedicum Helsinki; Helsinki Finland

23. Leibniz Institute for Age Research; Jena Germany

24. Oregon Health and Science University; Portland Oregon

25. University of Utah; Salt Lake City Utah

26. Clinical Genetics Branch; Division of Cancer Epidemiology and Genetics; National Cancer Institute; Rockville Maryland

27. Children's Hospital; Boston Massachusetts

28. Children's Tumor Foundation; New York New York

Publisher

Wiley

Subject

Genetics (clinical),Genetics

Reference70 articles.

1. Academies IoMotN 2012 Evolution of translational omics: Lessons learned and the path forward www.iom.edu/translationalomics

2. Dissecting and targeting the growth factor-dependent and growth factor-independent extracellular signal-regulated kinase pathway in human schwannoma;Ammoun;Cancer Res,2008

3. ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma;Ammoun;Neuro Oncol,2010a

4. Targeting ERK1/2 activation and proliferation in human primary schwannoma cells with MEK1/2 inhibitor AZD6244;Ammoun;Neurobiol Dis,2010b

5. Axl/Gas6/NFkappaB signalling in schwannoma pathological proliferation, adhesion and survival;Ammoun;Oncogene.,2013

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