A novel microtubule depolymerizing colchicine analogue triggers apoptosis and autophagy in HCT-116 colon cancer cells

Author:

Kumar Ashok12,Singh Baljinder23,Sharma Parduman R.12,Bharate Sandip B.24,Saxena Ajit K.5,Mondhe D. M.12

Affiliation:

1. Cancer Pharmacology Division; Indian Institute of Integrative Medicine (CSIR); Jammu India

2. Academy of Scientific and Innovative Research (AcSIR); Indian Institute of Integrative Medicine (CSIR); Jammu India

3. Natural Products Chemistry Division; Indian Institute of Integrative Medicine (CSIR); Jammu India

4. Medicinal Chemistry Division; CSIR-Indian Institute of Integrative Medicine; Jammu India

5. Amity University; Lucknow Uttar Pradesh India

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,General Medicine,Biochemistry

Reference43 articles.

1. Ferlay J Soerjomataram I Ervi M et al GLOBOCAN v1.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 11 International Agency for Research on Cancer Lyon, France 2013

2. Hallmarks of cancer: the next generation;Hanahan;Cell,2011

3. Autophagy in the pathogenesis of disease;Levine;Cell,2008

4. Classification of cell death: recommendations of the nomenclature committee on cell death;Kroemer;Cell Death Differ,2005

5. Promotion of tumorigenesis by heterozygous disruption of the beclin1 autophagy gene;Qu;J Clin Invest,2003

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