An alternative and robust synthesis of [13C4]Baraclude® (entecavir)-Reference-Cited by-同舟云学术

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An alternative and robust synthesis of [13C4]Baraclude® (entecavir)

Published:2013-07-16 Issue:12 Volume:56 Page:632-636
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J. Label Compd. Radiopharm

Author:

Easter John A.¹,Burrell Richard C.¹,Bonacorsi Samuel J.²

Affiliation:

1. Radiochemical Synthesis Group; Bristol-Myers Squibb Research and Development; 5 Research Parkway Wallingford CT 06492 USA

2. Radiochemical Synthesis Group; Bristol-Myers Squibb Research and Development; Route 206 and Province Line Road Princeton NJ 08543 USA

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.3064/fullpdf

Reference18 articles.

1. World health Organization Hepatitis B. World Health Organization Fact Sheet 204 2008 http://who.int/mediacntre/factsheets/fs204/en/fact204.html

2. Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus

3. Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection

4. A phase II study of entecavir vs lamivudine in adults with chronic hepatitis B

5. Synthesis of [13C4]Baraclude®(entecavir)

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