A Colon‐Targeted Adsorbent (DAV132) Does Not Affect the Pharmacokinetics of Warfarin or Clonazepam in Healthy Subjects-Reference-Cited by-同舟云学术

A Colon‐Targeted Adsorbent (DAV132) Does Not Affect the Pharmacokinetics of Warfarin or Clonazepam in Healthy Subjects

Published:2021-01-12 Issue:8 Volume:10 Page:908-917
ISSN:2160-763X
Container-title:Clinical Pharmacology in Drug Development
language:en
Short-container-title:Clinical Pharmacology in Drug Development

Author:

Pinquier Jean‐Louis¹,Varastet Marina²,Meyers Dismas³,Sayah‐Jeanne Sakina²,Féger Céline²⁴,Gaumétou Olivia²,Corbel Tanguy²,Gunzburg Jean²,Mentré France⁵,Ducher Annie²

Affiliation:

1. DECISIONS R&D Consulting Clamart France

2. Da Volterra Paris France

3. Medpace Clinical Pharmacology Unit Cincinnati Ohio USA

4. EMIBiotech Paris France

5. Université de Paris IAME INSERM Paris France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.901

Reference20 articles.

1. Protection of the Human Gut Microbiome From Antibiotics

2. Targeted adsorption of molecules in the colon with the novel adsorbent-based Medicinal Product, DAV132: A proof of concept study in healthy subjects

3. DucherA MentreF DonazzoloY et al.Dose‐effect and safety of DAV132 an activated charcoal based product when given with oral moxifloxacin on free moxifloxacin fecal concentrations and intestinal microbiota diversity: a randomized controlled trial (RCT) in 144 healthy volunteers (HVs). Poster presented at: ECCMID; April 21‐24 2018; Madrid Spain.

4. Modeling the Effect of DAV132, a Novel Colon‐Targeted Adsorbent, on Fecal Concentrations of Moxifloxacin and Gut Microbiota Diversity in Healthy Volunteers

5. Clonazepam Pharmacokinetics: Comparison of Subcutaneous Microsphere Injection With Multiple-Dose Oral Administration

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1. An open randomized multicentre Phase 2 trial to assess the safety of DAV132 and its efficacy to protect gut microbiota diversity in hospitalized patients treated with fluoroquinolones;Journal of Antimicrobial Chemotherapy;2022-01-07

2. Microbiome-pathogen interactions drive epidemiological dynamics of antibiotic resistance: A modeling study applied to nosocomial pathogen control;ELIFE;2021

3. Microbiome-pathogen interactions drive epidemiological dynamics of antibiotic resistance: A modeling study applied to nosocomial pathogen control;eLife;2021-09-14