Development and validation of an LC-MS/MS method for the determination of tigecycline in human plasma and cerebrospinal fluid and its application to a pharmacokinetic study

Author:

Mei Shenghui12,Luo Xuying3,Li Xingang12,Li Qian3,Huo Jiping1,Yang Li12,Zhu Leting1,Feng Weixing4,Zhou Jianxin3,Shi Guangzhi3,Zhao Zhigang12

Affiliation:

1. Department of Pharmacy, Beijing Tiantan Hospital; Capital Medical University; 6 TiantanXili, Dongcheng District Beijing 100050 People's Republic of China

2. Department of Clinical Pharmacology, College of Pharmaceutical Sciences; Capital Medical University; Beijing 100045 People's Republic of China

3. Intensive Care Unit, Beijing Tiantan Hospital; Capital Medical University; 6 TiantanXili, Dongcheng District Beijing 100050 People's Republic of China

4. Department of Neurology, Beijing Children's Hospital; Capital Medical University; Beijing 100045 People's Republic of China

Funder

Capital Medical University

National Natural Science Foundation of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference34 articles.

1. The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: Analysis of pooled clinical trial data;Babinchak;Clinical Infectious Diseases: an Official Publication of the Infectious Diseases Society of America,2005

2. In vitro activity of tigecycline against isolates from patients enrolled in phase 3 clinical trials of treatment for complicated skin and skin-structure infections and complicated intra-abdominal infections;Bradford;Clinical Infectious Diseases: an Official Publication of the Infectious Diseases Society of America,2005

3. The methodology and pharmacokinetics study of intraventricular administration of vancomycin in patients with intracranial infections after craniotomy;Chen;Journal of Critical Care,2015

4. Effect of the anticoagulant ethylenediamine tetra-acetic acid (EDTA) on the estimation of pharmacokinetic parameters: A case study with tigecycline and ciprofloxacin;Chen;Xenobiotica,2008

5. Steady-state serum and intrapulmonary pharmacokinetics and pharmacodynamics of tigecycline;Conte;International Journal of Antimicrobial Agents,2005

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3