A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell‐of‐origin dependent effects of H3K27M

Author:

Tomita Yusuke12ORCID,Shimazu Yosuke1ORCID,Somasundaram Agila3,Tanaka Yoshihiro45,Takata Nozomu67,Ishi Yukitomo1,Gadd Samantha8,Hashizume Rintaro139,Angione Angelo10,Pinero Gonzalo10,Hambardzumyan Dolores10,Brat Daniel J.11,Hoeman Christine M.1,Becher Oren J.13912ORCID

Affiliation:

1. Department of Pediatrics Feinberg School of Medicine, Northwestern University Chicago Illinois USA

2. Department of Neurosurgery and Neuroendovascular Surgery Hiroshima City Hiroshima Citizens Hospital Hiroshima Japan

3. Division of Hematology, Oncology and Stem Cell Transplant Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois USA

4. Department of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA

5. Center for Arrhythmia Research, Department of Cardiology Northwestern University Feinberg School of Medicine Chicago Illinois USA

6. Center for Vascular and Developmental Biology Feinberg Cardiovascular and Renal Research Institute (FCVRRI), Northwestern University Chicago Illinois USA

7. Simpson Querrey Institute for BioNanotechnology Northwestern University Chicago Illinois USA

8. Department of Pathology Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois USA

9. Department of Biochemistry and Molecular Genetics Feinberg School of Medicine, Northwestern University Chicago Illinois USA

10. Department of Neurosurgery and Oncological Sciences Mount Sinai School of Medicine New York USA

11. Department of Pathology Feinberg School of Medicine, Northwestern University Chicago Illinois USA

12. Jack Martin Division of Pediatric Hematology‐oncology Mount Sinai Kravis Children's Hospital New York USA

Funder

Foundation for the National Institutes of Health

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

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