Utilizing hydrolases of opposite enantiopreference for the preparation of both enantiomers of (1R,7aR)-(?)- and (1S,7aS)-(+)-3,6,7,7a-tetrahydro-1-hydroxy-7a-methyl-1H-inden-5(2H)-one
Author:
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/chir.20023/fullpdf
Reference27 articles.
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2. Biotransformations in organic chemistry, 4th ed. Berlin: Springer; 2000.
3. A Structural Basis for the Chiral Preferences of Lipases
4. How can the solvent affect enzyme enantioselectivity?
5. A structure-based rationalization of the enantiopreference of subtilisin toward secondary alcohols and isosteric primary amines
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