Low Levels of Hepatocyte‐Specific Methylation in cfDNA are a Strong Negative Predictor for Acute T‐cell Mediated Rejection requiring Treatment following Liver Transplantation

Author:

Cox Daniel R.A.123ORCID,Low Nicholas12,Goh Su Kah2,Lee Eunice2,Vago Angela4,Jackett Louise5,Lokan Julie5,Braat Sabine67,Jones Robert124,Testro Adam4,Dobrovic Alexander3,Muralidharan Vijayaragavan12

Affiliation:

1. The University of Melbourne Department of Surgery – Austin Precinct, Austin Hospital Studley Rd Heidelberg Melbourne Victoria 3084 Australia

2. HPB & Transplant Surgery Unit Department of Surgery Austin Hospital Studley Rd Heidelberg Melbourne Victoria 3084 Australia

3. Translational Genomics and Epigenomics Laboratory Department of Surgery University of Melbourne Austin Hospital Studley Rd, Heidelberg Melbourne Victoria 3084 Australia

4. Liver Transplant Unit Department of Gastroenterology & Hepatology Austin Hospital Studley Rd Heidelberg Melbourne Victoria 3084 Australia

5. Department of Anatomical Pathology Austin Hospital Heidelberg VIC Australia

6. Centre for Epidemiology and Biostatistics School of Population and Global Health The University of Melbourne Melbourne Australia

7. MISCH (Methods and Implementation Support for Clinical Health research hub) Faculty of Medicine, Dentistry and Health Sciences The University of Melbourne Melbourne Australia

Publisher

Wiley

Subject

Transplantation,Hepatology,Surgery

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