Afraid and tired: A longitudinal study of the relationship between cancer‐related fatigue and fear of cancer recurrence in long‐term cancer survivors

Author:

Trudel Geneviève1,Lebel Sophie1ORCID,Stephens Robert L.2,Leclair Caroline Séguin1,Leach Corinne R.3,Westmaas J. Lee4

Affiliation:

1. School of Psychology University of Ottawa Ottawa Ontario Canada

2. ICF International Inc Atlanta Georgia USA

3. Moffit Cancer Center Tampa Florida USA

4. American Cancer Society Atlanta Georgia USA

Abstract

AbstractObjectiveCancer‐related fatigue (CRF) and fear of cancer recurrence (FCR) are two common concerns experienced by cancer survivors. However, the relationship between these two concerns is poorly understood, and whether CRF and FCR influence each other over time is unclear.MethodsData were from a national, prospective, longitudinal study, the American Cancer Society's Study of Cancer Survivors‐I (SCS‐I). Surveys were completed by 1395 survivors of 10 different cancer types at three time‐points, including assessment 1.3 years (T1), 2.2 years (T2) and 8.8 years (T3) following their cancer diagnosis. CRF was assessed using the fatigue‐inertia subscale of the Profile of Mood States, and FCR by the FCR subscale of the Cancer Problems in Living Scale. Multiple group random intercepts cross‐lagged panel models investigated prospective associations between CRF and FCR.ResultsFor younger participants (at or below median age of 55 years, n = 697), CRF at T1 and T2 marginally and significantly predicted FCR at T2 and T3, respectively, but no lagged effects of FCR on subsequent CRF were observed. Cross‐lagged effects were not observed for survivors over 55 years of age.ConclusionBoth CRF and FCR are debilitating side effects of cancer and its treatments. Given that CRF may be predictive of FCR, it possible that early detection and intervention for CRF could contribute to lowering FCR severity.

Funder

American Cancer Society

Publisher

Wiley

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