An outbreak of a novel lineage of dengue virus 2 in Vietnam in 2022

Author:

Nabeshima Takeshi12,Ngwe Tun Mya Myat13ORCID,Thuy Nguyen Thi Thu4,Hang Nguyen Le Khanh4,Mai Le Thi Quynh4,Hasebe Futoshi5,Takamatsu Yuki16,

Affiliation:

1. Department of Virology Institute of Tropical Medicine, Nagasaki University (ITM‐NU) Nagasaki Japan

2. Kenya Research Station Institute of Tropical Medicine, Nagasaki University Nagasaki Japan

3. DEJIMA Infectious Disease Research Alliance Nagasaki University Nagasaki Japan

4. Department of Virology National Institute of Hygiene and Epidemiology Hanoi Vietnam

5. Vietnam Research Station Institute of Tropical Medicine, Nagasaki University Nagasaki Japan

6. Graduate School of Biomedical Sciences Nagasaki University Nagasaki Japan

Abstract

AbstractIn 2022, a large dengue outbreak was reported in Vietnam, where dengue was endemic. A total of 1889 acute‐phase serum samples were collected from patients with suspected dengue at Vung Tau General Hospital, the core hospital in Vung Tau Province, southern Vietnam. Among the 1889 samples analyzed for laboratory confirmation of dengue virus (DENV) infection, 339 positive cases were identified, of which 130 were primary infections and 209 were secondary infections. DENV‐2 was the dominant serotype in both primary and secondary infection groups. Phylogenetic analysis based on sequences of the envelope protein‐coding region revealed the emergence of a new DENV‐2 lineage during this outbreak.

Publisher

Wiley

Subject

Infectious Diseases,Virology

Reference15 articles.

1. WHO.Dengue Guidelines For Diagnosis Treatment Prevention and Control.2009.https://www.who.int/publications/i/item/9789241547871

2. WHO.Dengue in Viet Nam.2022.https://www.who.int/vietnam/health-topics/dengue

3. WHO.Dengue and Severe Dengue.2022.https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue

4. Time to Harmonize Dengue Nomenclature and Classification

5. A phylogenetic study of dengue virus in urban Vietnam shows long-term persistence of endemic strains

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