Linalool attenuated ischemic injury in PC12 cells through inhibition of caspase‐3 and caspase‐9 during apoptosis

Author:

Hosseini Azar12,Pourheidar Elham3,Rajabian Arezoo4ORCID,Asadpour Elham5,Hosseinzadeh Hossein6ORCID,Sadeghnia Hamid Reza127ORCID

Affiliation:

1. Pharmacological Research Center of Medicinal Plants Mashhad University of Medical Sciences Mashhad Iran

2. Department of Pharmacology Faculty of Medicine, Mashhad University of Medical Sciences Mashhad Iran

3. Department of Intensive Care Unit Hazrat Rasul akram Hospital Iran University of Medical Sciences Tehran Iran

4. Department of Internal Medicine, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran

5. Anesthesiology and Critical Care Research Center Shiraz University of Medical Sciences Shiraz Iran

6. Pharmaceutical Research Center Pharmaceutical Technology Institute Mashhad University of Medical Sciences Mashhad Iran

7. Division of Neurocognitive Sciences, Psychiatry and Behavioral Sciences Research Center Mashhad University of Medical Sciences Mashhad Iran

Funder

Mashhad University of Medical Sciences

Publisher

Wiley

Subject

Food Science

Reference64 articles.

1. Linalool protects hippocampal CA1 neurons and improves functional outcomes following experimental ischemia/reperfusion in rats;Airao V.;Journal of Applied Biology and Biotechnology,2021

2. Effects of combinations of curcumin, linalool, rutin, safranal, and thymoquinone on glucose/serum deprivation‐induced cell death;Alinejad B.;Avicenna Journal of Phytomedicine,2013

3. Anxiolytic and Anticonvulsant Effects on Mice of Flavonoids, Linalool, and -Tocopherol Presents in the Extract of Leaves ofCissus sicyoidesL. (Vitaceae)

4. Hepatoprotective Activity of Linalool in Rats Against Liver Injury Induced by Carbon Tetrachloride

5. Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress

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