Feasible Synthesis of N,O‐Bidentate Difluoroboron Chromophores through Direct Functionalization of Quinoxalin‐2(1H)‐ones with Ketones in One Shot

Author:

Zhang Shuaichen1,Zhang Jing1,Ling Xiang2,Zhao Yifan1,Ma Yue1,Sun Peng1

Affiliation:

1. State Key Laboratory for Quality Ensurance and Sustainable Use of Dao‐di Herbs; Artemisinin Research Center and Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing 100700 China

2. Department of Pharmaceutics, School of Pharmacy China Pharmaceutical University, State Key Laboratory of Natural Medicines Nanjing Jiangsu 210009 China

Abstract

Comprehensive SummaryOrganic difluoroboron complexes are a kind of potential platforms for a wide range of applications owing to their excellent photophysical properties. Herein, we have explored a simple and direct synthesis methodology for a library of N,O‐bidentate difluoroboron complexes from quinoxalin‐2(1H)‐ones and ketones in one shot. The photophysical properties of the generated complexes were evaluated and the application potential of these compounds on subcellular imaging was also explored.

Publisher

Wiley

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