Physiologically Based Pharmacokinetic Models for Adults and Children Reveal a Role of Intracellular Tubulin Binding in Vincristine Disposition-Reference-Cited by-同舟云学术

Physiologically Based Pharmacokinetic Models for Adults and Children Reveal a Role of Intracellular Tubulin Binding in Vincristine Disposition

Published:2019-08-30 Issue:10 Volume:8 Page:759-768
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Lee Christine M.¹,Zane Nicole R.²,Veal Gareth³,Thakker Dhiren R.¹

Affiliation:

1. Division of Pharmacotherapy and Experimental Therapeutics UNC Eshelman School of Pharmacy The University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

2. The Center for Clinical Pharmacology at The Children's Hospital of Philadelphia Philadelphia Pennsylvania USA

3. Northern Institute for Cancer Research Newcastle University Newcastle upon Tyne UK

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12453

Reference44 articles.

1. Childhood and adolescent cancer statistics, 2014

2. Acute lymphoblastic leukaemia

3. Vincristine revisited

4. Peripheral Neuropathy with Microtubule-Targeting Agents: Occurrence and Management Approach

5. Pharmacokinetics of vincristine in children and adolescents with acute lymphocytic leukemia

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