A Minimal Physiologically‐Based Pharmacokinetic Model for Tacrolimus in Living‐Donor Liver Transplantation: Perspectives Related to Liver Regeneration and the cytochrome P450 3A5 (CYP3A5) Genotype-Reference-Cited by-同舟云学术

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A Minimal Physiologically‐Based Pharmacokinetic Model for Tacrolimus in Living‐Donor Liver Transplantation: Perspectives Related to Liver Regeneration and the cytochrome P450 3A5 (CYP3A5) Genotype

Published:2019-06-09 Issue:8 Volume:8 Page:587-595
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Itohara Kotaro¹²,Yano Ikuko¹³,Tsuzuki Tetsunori¹,Uesugi Miwa¹,Nakagawa Shunsaku¹,Yonezawa Atsushi¹²^ORCID,Okajima Hideaki⁴,Kaido Toshimi⁴,Uemoto Shinji⁴,Matsubara Kazuo¹

Affiliation:

1. Department of Clinical Pharmacology and Therapeutics Kyoto University Hospital Kyoto Japan

2. Graduate School of Pharmaceutical Sciences Kyoto University Kyoto Japan

3. Department of Pharmacy Kobe University Hospital Kobe Japan

4. Division of Hepato‐Biliary‐Pancreatic Surgery and Transplantation Department of Surgery Graduate School of Medicine Kyoto University Kyoto Japan

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12420

Reference45 articles.

1. Clinical Pharmacokinetics of Tacrolimus

2. Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation

3. An up-date review on individualized dosage adjustment of calcineurin inhibitors in organ transplant patients

4. Therapeutic drug monitoring of immunosuppressant drugs in clinical practice

5. Effect of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors: Part I

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2. A model-based pharmacokinetic assessment of drug–drug interaction between tacrolimus and nirmatrelvir/ritonavir in a kidney transplant patient with COVID-19;Drug Metabolism and Pharmacokinetics;2023-12

3. A Physiologically Based Pharmacokinetic Approach to Recommend an Individual Dose of Tacrolimus in Adult Heart Transplant Recipients;Pharmaceutics;2023-11-03

4. Physiologically-based pharmacokinetic modeling-guided rational combination of tacrolimus and voriconazole in patients with different CYP3A5 and CYP2C19 alleles;Toxicology and Applied Pharmacology;2023-05

5. Extrapolation of physiologically based pharmacokinetic model for tacrolimus from renal to liver transplant patients;Drug Metabolism and Pharmacokinetics;2022-02

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