Quantitative Systems Pharmacology: An Exemplar Model‐Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development-Reference-Cited by-同舟云学术

Quantitative Systems Pharmacology: An Exemplar Model‐Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development

Published:2019-06 Issue:6 Volume:8 Page:380-395
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Helmlinger Gabriel¹,Sokolov Victor²,Peskov Kirill²³,Hallow Karen M.⁴⁵,Kosinsky Yuri²,Voronova Veronika²,Chu Lulu¹,Yakovleva Tatiana²,Azarov Ivan²,Kaschek Daniel⁶,Dolgun Artem²,Schmidt Henning⁶,Boulton David W.⁷,Penland Robert C.¹

Affiliation:

1. Quantitative Clinical PharmacologyEarly Clinical DevelopmentIMED Biotech UnitAstraZeneca Pharmaceuticals Boston Massachusetts USA

2. M&S Decisions LLC Moscow Russia

3. Computational Oncology GroupI.M. Sechenov First Moscow State Medical University of the Russian Ministry of Health Moscow Russia

4. School of Chemical, Materials, and Biomedical EngineeringUniversity of Georgia Athens Georgia USA

5. Department of Epidemiology and BiostatisticsUniversity of Georgia Athens Georgia USA

6. IntiQuan GmbH Basel Switzerland

7. Quantitative Clinical PharmacologyEarly Clinical DevelopmentIMED Biotech UnitAstraZeneca Pharmaceuticals Gaithersburg Maryland USA

Funder

AstraZeneca

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12426

Reference89 articles.

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4. FDA Advisory Meeting Clinical Pharmacology Review Utilizes a Quantitative Systems Pharmacology (QSP) Model: A Watershed Moment?

5. Quantitative Systems Pharmacology: A Case for Disease Models

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