Dose‐finding designs using a novel quasi‐continuous endpoint for multiple toxicities-Reference-Cited by-同舟云学术

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Dose‐finding designs using a novel quasi‐continuous endpoint for multiple toxicities

Published:2013-01-21 Issue:16 Volume:32 Page:2728-2746
ISSN:0277-6715
Container-title:Statistics in Medicine
language:en
Short-container-title:Statist. Med.

Author:

Ezzalfani Monia¹,Zohar Sarah²³,Qin Rui⁴,Mandrekar Sumithra J.⁴,Deley Marie‐Cécile Le¹⁴⁵

Affiliation:

1. Biostatistics Department Institut Gustave‐Roussy Villejuif France

2. INSERM, U717 Biostatistics Department Paris France

3. INSERM, U872, Centre de Recherche des Cordeliers Université Paris 5, Université Paris 6 Paris France

4. Mayo Clinic Rochester, MN U.S.A.

5. Université Paris‐Sud 11 Paris France

Publisher

Wiley

Subject

Statistics and Probability,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.5737

Reference35 articles.

1. Nature and subjectivity of dose-limiting toxicities in contemporary phase 1 trials: comparison of cytotoxic versus non-cytotoxic drugs

2. Current challenges for the early clinical development of anticancer drugs in the era of molecularly targeted agents

3. A novel toxicity scoring system treating toxicity response as a quasi-continuous variable in Phase I clinical trials

4. Dose-Finding Based on Multiple Toxicities in a Soft Tissue Sarcoma Trial

5. Validation of toxicity burden score for use in phase I clinical trials;Lee SM;Journal of Clinical Oncology (ASCO Annual Meeting),2010

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