Comparison of purity and enrichment of CD34 + cells from bone marrow, umbilical cord and peripheral blood (primed for apheresis) using five separation systems

Author:

De Wynter E. A.1,Coutinho L. H.1,Pei X.1,Marsh J. C. W.1,Hows J.1,Luft T.1,Testa N. G.1

Affiliation:

1. Cancer Research Campaign Department of Experimental Haematology, Paterson Institute for Cancer Research, Manchester, United Kingdom

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Molecular Medicine

Reference23 articles.

1. Positive cell selection – basic science;Civin CI;Prog Clin Biol Res,1990

2. Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma

3. ShpallEJ JonesRB FranklinWet al.CD34 positive marrow and/or peripheral blood progenitor cells (PBPC) provide effective haemopoietic reconstitution of breast cancer patients following high‐dose chemotherapy with autologous haemopoietic progenitor cell support34th Annual American Society of Hematology Meeting Anaheim California December 4–8. Blood1992; 80(suppl 1):24a.

4. Positive selection of haemopoietic CD34+ stem cells provides “indirect” purging of CD34− lymphoid cells and the purging efficiency is increased by anti‐CD2 and anti‐CD30 immunotoxins;Lemoli RM;Bone Marrow Transplant,1994

5. Ex vivo expansion of enriched peripheral blood CD34+ progenitor cells by stem cell factor, interleukin 1β (IL‐1β), IL6, IL3, interferon‐γ and erythropoietin;Brugger W;Blood,1993

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