Validated LC-MS/MS method for quantification of agomelatine in human plasma and its application in a pharmacokinetic study

Author:

Patil Satish R.,Nerurkar Ketan K.1,Kalamkar Ashok M.1,Pukale Vishwas,Mangaonkar Kiran V.2,Pingale Satish G.2

Affiliation:

1. Drug Monitoring Research Institute; Rabale; 400701; Navi Mumbai; India

2. Analytical Chemistry Research Laboratory, Mithibai College of Arts; Chauhan Institute of Science & Amrutben Jivanlal College of Commerce and Economics; Vile Parle (W); Mumbai; 400056; India

Publisher

Wiley

Subject

Spectroscopy

Reference6 articles.

1. Clinical and pharmacological review on novel melatonergic antidepressant: agomelatine;Venkat Rao;Res. J. Pharm. Biol. Chem. Sci.,2010

2. Pilot study comparing in blind the therapeutic effect of two doses of agomelatine, melatonin-agonist and selective 5HT2c receptors antagonist, in the treatment of major depressive disorders;Lôo;Encéphale,2003

3. N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide, a potent melatonin analog;Tinant;Acta Cryst.,1994

4. Determination of agomelatine by RP-HPLC;Xue jun;West Chin. J. pharm. sci.,2010

5. Guideline on the investigation of bioequivalence 2010 13

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