The absorption kinetics of ketoconazole plays a major role in explaining the reported variability in the level of interaction with midazolam: Interplay between formulation and inhibition of gut wall and liver metabolism-Reference-Cited by-同舟云学术

The absorption kinetics of ketoconazole plays a major role in explaining the reported variability in the level of interaction with midazolam: Interplay between formulation and inhibition of gut wall and liver metabolism

Published:2017-02-14 Issue:3 Volume:38 Page:260-270
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Liu Bo¹,Crewe H. Kim¹,Ozdemir Mahmut²,Rowland Yeo Karen¹,Tucker Geoffrey³,Rostami-Hodjegan Amin¹⁴^ORCID

Affiliation:

1. Simcyp Ltd, Blades Enterprise Centre; John Street Sheffield S2 4SU UK

2. Department of Pharmacology, Faculty of Medicine; Eskişehir Osmangazi University; Eskişehir Turkey

3. Department of Human Metabolism (Emeritus), Medicine and Biomedical Sciences; University of Sheffield; Sheffield S10 2JF UK

4. Manchester Pharmacy School; Stopford Building, Oxford Road Manchester M13 9PT UK

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference33 articles.

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3. pH-dependent dissolution in vitro and absorption in vivo of weakly basic drugs: development of a canine model;Zhou;Pharm Res,2005

4. Clinical pharmacokinetics of systemic antifungal drugs;Daneshmend;Clin Pharmacokinet,1983

5. Pharmacokinetics of ketoconazole in normal subjects;Daneshmend;J Antimicrob Chemother,1981

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