Oxygen gradient ektacytometry‐derived biomarkers are associated with vaso‐occlusive crises and correlate with treatment response in sickle cell disease

Author:

Rab Minke A. E.12ORCID,Kanne Celeste K.3,Bos Jennifer1,Oirschot Brigitte A.1,Boisson Camille45,Houwing Maite E.6,Gerritsma Jorn7,Teske Erik8,Renoux Celine459,Riedl Jurgen10,Schutgens Roger E. G.2,Bartels Marije2,Nur Erfan11,Joly Philippe459,Fort Romain12,Cnossen Marjon H.6,Wijk Richard1,Connes Philippe45,Beers Eduard J.2,Sheehan Vivien A.3ORCID

Affiliation:

1. Central Diagnostic Laboratory‐Research University Medical Center Utrecht, Utrecht University Utrecht The Netherlands

2. Van Creveldkliniek, University Medical Center Utrecht Utrecht University Utrecht The Netherlands

3. Department of Pediatrics Emory University School of Medicine Childrenʼs Healthcare of Atlanta Atlanta Georgia USA

4. Laboratory LIBM EA7424, University of Lyon 1, “Vascular Biology and Red Blood Cell” team Lyon France

5. Laboratory of Excellence GR‐Ex Paris France

6. Department of Pediatric Hematology Erasmus Medical Center Rotterdam The Netherlands

7. Emma Childrenʼs Hospital, Pediatric Hematology Amsterdam University Medical Centers Amsterdam The Netherlands

8. Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands

9. Laboratory of Biochemistry and Molecular Biology, UF Biochemistry of Red Blood Cell diseases, Est Center of Biology and Pathology Hospices Civils de Lyon Lyon France

10. Result Laboratory Albert Schweitzer Hospital Dordrecht The Netherlands

11. Department of Hematology Amsterdam University Medical Centers Amsterdam The Netherlands

12. Department of Internal Medicine Hospices Civils de Lyon Lyon France

Funder

Eurostars

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Wiley

Subject

Hematology

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