Development and validation of automated SPE-LC-MS/MS method for determination of indapamide in human whole blood and its application to real study samples

Author:

Nakov N.1,Mladenovska K.1,Labacevski N.2,Dimovski A.1,Petkovska R.1,Dimitrovska A.1,Kavrakovski Z.1

Affiliation:

1. Faculty of Pharmacy; University of ‘Ss Cyril and Methodius’; Skopje; Republic of Macedonia

2. Institute of Preclinical and Clinical Pharmacology and Toxicology, Medical Faculty; University of ‘Ss Cyril and Methodius’; Skopje; Republic of Macedonia

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference13 articles.

1. Validation of bioanalytical LC-MS/MS assays: Evaluation of matrix effects;Eeckhaut;Journal of Chromatography B,2009

2. European Medicines Agency Guideline on Validation of Bioanalytical Methods 2011 http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2011/08/WC500109686.pdf

3. A selective HPLC method for the determination of indapamide in human whole blood: application to a bioequivalence study in Chinese volunteers;Hang;Journal of Pharmaceutical and Biomedical Analysis,2006

4. Liquid chromatography-tandem mass spectrometry validated method for estimation of indapamide in human whole blood;Jain;Journal of Chromatography B,2006

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