Determination and pharmacokinetics of linarin in rat plasma after intramuscular administration of linarin solution and Yejuhua injection by HPLC

Author:

Zhao Xu1,Mao Xin1,Xu Xuan1,Li Xiaolong1,Bi Kaishun2,Jia Ying1

Affiliation:

1. Shenyang Key Laboratory of Active Components of Chinese Medicine Screening and Evaluation, School of Traditional Chinese Materia Medica; Shenyang Pharmaceutical University; Wenhua Road 103 Shenyang 110016 China

2. The Engineering Laboratory of National and Local Union of Quality Control for Traditional Chinese Medicine, School of Pharmacy; Shenyang Pharmaceutical University; Wenhua Road 103 Shenyang 110016 China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference10 articles.

1. Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis;Fernández;Pharmacology Biochemistry and Behavior,2004

2. RP-HPLC determination of linarin in beagle dog plasma after administration of Yejuhua injection;Jia;Chromatographia,2006

3. Linarin isolated from Buddleja officinalis prevents hydrogen peroxide-induced dysfunction in osteoblastic MC3T3-E1 cells;Kim;Cellular Immunology,2011

4. Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-b-induced neuronal cell death Bioorganic Medicine and;Lou;Chemistry,2011

5. Determination of chlorogenic acid in injection of Flos Chrysanthemi Indici by HPLC;Luo;Drug Evaluation,2006

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