Affiliation:
1. Department of Oral and Maxillofacial Pathology Neuron Institute of Applied Research Amravati India
2. Center for Global Health Research Saveetha Medical College Saveetha Institute of Medical and Technical Sciences Chennai Tamil Nadu India
3. Department of Medical Sciences School of Medical and Life Sciences Sunway University Bandar Sunway Subang Jaya Malaysia
Abstract
AbstractMilk exosomes, extracellular nanovesicles that are naturally present in milk, have gained significant attention in cancer research for their potential to revolutionize cancer treatment strategies. They possess a specific set of characteristics that make them promising nanoscale vehicles for targeted drug delivery systems. Their inherent biocompatibility, coupled with their ability to effectively encapsulate and transport therapeutic agents directly into tumor cells, suggests the possibility of developing novel cancer therapies, potentially minimizing side effects associated with conventional therapies. However, recent studies have shown that milk exosomes have a dual nature, which is not entirely positive. Although they show potential in delivering anticancer therapeutics, evidence suggests they may also, under certain conditions, contribute to cancer progression. This paradoxical nature necessitates a better understanding of how they interact and work in different stages of cancer. Further investigation is crucial to understand the factors influencing their behaviour and to develop strategies that can maximize their therapeutic prospects while mitigating potential risks associated with their use in cancer treatment.