Antibacterial Activity of Carboxymethyl Chitosan Dialdehyde Starch Schiff Base and its Metal Complex

Author:

Ouyang Jinyu1,Li Zhenbiao1ORCID,Miao Jincheng1,Wang Yongtao1,Hu Langrong1,Wang Xiaojuan1

Affiliation:

1. Guangxi Key Laboratory of Electrochemical and Magneto‐chemical Function Materia College of Chemistry and Bioengineering Guilin University of Technology Guilin 541004 China

Abstract

AbstractCarboxymethyl chitosan dialdehyde starch Schiff base (CMCDAS) and its metal complexes are synthesized by corn starch (St), sodium periodate, carboxymethyl chitosan, and metal ions (copper, zinc, nickel, silver), and are characterized by Fourier transform infrared spectroscopy (FT‐IR), scanning electron microscopy (SEM), thermogravimetric analyzer (TGA), energy dispersive spectroscopy (EDS), and X‐ray powder diffraction (XRD). The antibacterial activities of carboxymethyl chitosan dialdehyde starch Schiff base (CMCDAS) against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) increase according to their increasing nitrogen content, and the best minimum inhibitory concentrations (MIC) against E. coli and S. aureus are 30 mg mL−1, respectively. Furthermore, the minimum inhibitory concentrations (MIC) of the metal complexes (copper, nickel, silver, and zinc) against S. aureus are 7.50, 30, 30, and 1.88 mg mL, respectively; and against E. coli are 7.50, 15, 15, and 0.94 mg mL−1, respectively.

Publisher

Wiley

Subject

Organic Chemistry,Food Science

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