Sustained low‐dose interleukin‐2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus

Author:

Liang Kaili1,He Jing2,Wei Yunbo3,Zeng Qunxiong1,Gong Dongcheng1,Qin Jiahuan1,Ding Huihua45,Chen Zhian6,Zhou Ping4,Niu Peng4,Chen Qian7,Ding Chenguang8,Lu Liangjing5,Chen Xiao‐Xiang5,Li Zhanguo2,Shen Nan1459,Yu Di136,Deng Jun19ORCID

Affiliation:

1. China‐Australia Centre for Personalized Immunology Renji Hospital Shanghai Jiao Tong University School of Medicine (SJTUSM) Shanghai China

2. Department of Rheumatology and Immunology Peking University People's Hospital Beijing China

3. Laboratory of Immunology for Environment and Health School of Pharmaceutical Sciences Qilu University of Technology (Shandong Academy of Sciences) Jinan China

4. Shanghai Institute of Rheumatology Renji Hospital Shanghai Jiao Tong University School of Medicine (SJTUSM) Shanghai China

5. Department of Rheumatology Renji Hospital Shanghai Jiao Tong University School of Medicine (SJTUSM) Shanghai China

6. Faculty of Medicine The University of Queensland Diamantina Institute The University of Queensland Brisbane QLD Australia

7. Department of Ophthalmology Shanghai General Hospital (Shanghai First People's Hospital) School of Medicine Shanghai Jiao Tong University Shanghai China

8. Department of Kidney Transplantation Nephropathy Hospital the First Affiliated Hospital of Xi'an Jiaotong University Xi'an China

9. State Key Laboratory of Oncogenes and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiao Tong University School of Medicine (SJTUSM) Shanghai China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Nursing,Immunology,Immunology and Allergy

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