The therapeutic potential of typical plant‐derived compounds for the management of metabolic disorders

Author:

Roy Debajyoti12,Kaur Prabhjot3,Ghosh Maitrayee2,Choudhary Deepika4,Rangra Naresh Kumar5ORCID

Affiliation:

1. Department of Pharmacognosy ISF College of Pharmacy Moga Punjab India

2. Department of Pharmacy CV Raman Global University Bhubaneswar Odisha India

3. Department of Pharmaceutical Chemistry ISF College of Pharmacy Moga Punjab India

4. Department of Pharmaceutical Sciences and Natural Products Central University of Punjab Bathinda Punjab India

5. Chitkara School of Pharmacy Chitkara University Baddi Himachal Pradesh India

Abstract

AbstractObesity and Type 2 diabetes are prevalent metabolic dysfunctions that present significant health challenges worldwide. Available cures for these ailments have constraints with accompanying unwanted effects that persistently exist. Compounds originated from plants have recently been introduced as hopeful remedies to treat metabolic disorders because of their diverse pharmacological activities. This detailed observation gives an introduction into the treatment capacity of plant‐derived compounds regarding metabolic syndromes while analyzing various groups alongside their performance in this field despite unique mechanisms designed by nature itself. Interestingly, this study provides some examples including curcumin, resveratrol, quercetin, berberine, epigallocatechin gallate (EGCG), and capsaicin, which highlights potential therapeutic impacts for future testing. However, current clinical trials inspecting human studies investigating efficacies concerning metabolism challenge present limitations. Finally, the review weighs up bad reactions possibly inflicted after administering plant‐originated materials though suggestive insights will be provided later. Above all, it outlines the chance to identify novel therapies encapsulated within natural substances based upon recent developments could hold significant promise toward managing misplaced metabolisms globally.

Publisher

Wiley

Reference127 articles.

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4. American Association for Clinical Chemistry. (2022).Metabolic disorders.https://labtestsonline.org/conditions/metabolic-disorders

5. American Heart Association. (2021).Metabolic syndrome.https://www.heart.org/en/health‐topics/metabolic‐syndrome/treatment‐and‐prevention‐of‐metabolic‐syndrome

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