Glycan engineering reveals interrelated effects of terminal galactose and core fucose on antibody‐dependent cell‐mediated cytotoxicity-Reference-Cited by-同舟云学术

Glycan engineering reveals interrelated effects of terminal galactose and core fucose on antibody‐dependent cell‐mediated cytotoxicity

Published:2020-08-04 Issue:6 Volume:36 Page:
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnol Progress

Author:

Zhang Qingchun¹^ORCID,Joubert Marisa K.¹,Polozova Alla¹,De Guzman Ronandro¹,Lakamsani Kamala¹,Kinderman Francis²,Xiang Dong¹,Shami Andrew¹,Miscalichi Nahira¹,Flynn Gregory C.¹,Kuhns Scott¹

Affiliation:

1. Attribute Sciences, Amgen Inc. Thousand Oaks California USA

2. Drug Product Technologies, Amgen Inc. Thousand Oaks California USA

Publisher

Wiley

Subject

Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3045

Reference25 articles.

1. Glycosylation as a strategy to improve antibody-based therapeutics

2. Improving effector functions of antibodies for cancer treatment: enhancing ADCC and CDC;Natsume A;Drug Des Devel Ther,2009

3. Naturally occurring glycan forms of human immunoglobulins G1 and G2

4. Industry and regulatory experience of the glycosylation of monoclonal antibodies

5. Using glyco-engineering to produce therapeutic proteins

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