Affiliation:
1. School of Chemistry and Chemical Engineering Linyi University Linyi China
2. CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation Research Center for Coastal Environmental Engineering and Technology Yantai Institute of Coastal Zone Research Chinese Academy of Sciences Yantai China
Abstract
Deep eutectic solvents (DESs), as a new type of eco‐friendly solvent, have attracted increasing attention on the extraction and separation of flavonoid compounds from various samples, owing to their excellent properties such as biodegradability and ease of handling with very low toxicity. This article provides a status review of the applications of DESs in the extraction of flavonoids, including the introduction of flavonoid compounds, the properties and superiority of DESs, and extraction methods (ultrasonic‐assisted extraction, heating reflux extraction, matrix solid‐phase dispersion, and solid‐phase extraction). Finally, prospects and challenges in the application of DESs on extraction and separation are extensively elucidated and critically reviewed.
Funder
Natural Science Foundation of Shandong Province