Optimization of a multi-stage, multi-subunit malaria vaccine candidate for the production inPichia pastorisby the identification and removal of protease cleavage sites-Reference-Cited by-同舟云学术

Optimization of a multi-stage, multi-subunit malaria vaccine candidate for the production inPichia pastorisby the identification and removal of protease cleavage sites

Published:2014-11-24 Issue:4 Volume:112 Page:659-667
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Spiegel Holger¹,Schinkel Helga¹,Kastilan Robin¹,Dahm Pia¹,Boes Alexander¹,Scheuermayer Matthias²,Chudobová Ivana¹,Maskus Dominika¹,Fendel Rolf¹³,Schillberg Stefan¹,Reimann Andreas¹,Fischer Rainer¹³

Affiliation:

1. Fraunhofer Institute for Molecular Biology and Applied Ecology IME; Forckenbeckstrasse 6 Aachen 52074 Germany

2. Research Center for Infectious Diseases; University of Würzburg; Josef Schneider Str. 2/ Bau D15 Würzburg 97080 Germany

3. Institute for Molecular Biotechnology; RWTH Aachen University; Worringer Weg 1 Aachen 52074 Germany

Funder

Fraunhofer-Gesellschaft

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

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3. High-level production and purification of P30P2MSP1(19), an important vaccine antigen for malaria, expressed in the methylotropic yeast Pichia pastoris;Brady;Protein Expr Purif,2001

4. Secretion of recombinant human insulin-like growth factor I (IGF-I);Brierley;Methods Mol Biol,1998

5. Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae;Brake;Proc Natl Acad Sci U S A,1984

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