Interaction of picolinamide fungicide primary metabolites UK‐2A and CAS ‐649 with the cytochrome bc 1 complex Qi site: mutation effects and modelling in Saccharomyces cerevisiae
Author:
Affiliation:
1. Crop Protection Discovery and Development Corteva Agriscience Indianapolis IN USA
2. Institute for Integrative Biology of the Cell (I2BC), Université Paris‐Saclay, CEA, CNRS Gif‐sur‐Yvette France
Funder
Corteva Agriscience
Meiji Seika Pharma
Publisher
Wiley
Subject
Insect Science,Agronomy and Crop Science,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ps.6893
Reference36 articles.
1. Biological characterization of fenpicoxamid, a new fungicide with utility in cereals and other crops
2. UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. I. Fermentation, Isolation, and Biological Properties.
3. The Mode of Action of UK-2A and UK-3A, Novel Antifungal Antibiotics from Streptomyces sp. 517-02.
4. UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. V. Inhibition Mechanism of Bovine Heart Mitochondrial Cytochrome bc1 by the Novel Antibiotic UK-2A.
5. Discovery of florylpicoxamid, a mimic of a macrocyclic natural product
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1. The Interaction Mechanism of Picolinamide Fungicide Targeting on the Cytochrome bc1 Complex and Its Structural Modification;Journal of Agricultural and Food Chemistry;2024-02-12
2. Resistance risk and resistance-related point mutations in cytochrome b of florylpicoxamid in Colletotrichum scovillei;Pesticide Biochemistry and Physiology;2023-11
3. New chemical fungicides in relation to risk for resistance development;Tropical Plant Pathology;2023-07-19
4. Characterization of mutants with single and combined Qi and Qo site mutations in Saccharomyces cerevisiae reveals interactions between the picolinamide fungicide CAS-649 and azoxystrobin;Pesticide Biochemistry and Physiology;2023-01
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