Serotype chimeric oncolytic adenovirus coding for GM-CSF for treatment of sarcoma in rodents and humans

Author:

Bramante Simona1,Koski Anniina1,Kipar Anja23,Diaconu Iulia1,Liikanen Ilkka1,Hemminki Otto1,Vassilev Lotta4,Parviainen Suvi1,Cerullo Vincenzo15,Pesonen Saila K1,Oksanen Minna1,Heiskanen Raita4,Rouvinen-Lagerström Noora1,Merisalo-Soikkeli Maiju1,Hakonen Tiina4,Joensuu Timo6,Kanerva Anna17,Pesonen Sari1,Hemminki Akseli146

Affiliation:

1. Cancer Gene Therapy Group Department of Pathology and Transplantation Laboratory, Haartman Institute; University of Helsinki; Helsinki Finland

2. Finnish Centre for Laboratory Animal Pathology Faculty of Veterinary Medicine; University of Helsinki; Helsinki Finland

3. School of Veterinary Science and Department of Infection Biology; Institute of Global Health,University of Liverpool; Liverpool United Kingdom

4. Oncos Therapeutics Ltd.; Helsinki Finland

5. Laboratory of Immunovirotherapy Division of Biopharmaceutics and Pharmacokinetics Faculty of Pharmacy; University of Helsinki; Helsinki Finland

6. Docrates Cancer Center; Helsinki Finland

7. Department of Obstetrics and Gynecology; Helsinki University Central Hospital; Helsinki Finland

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference50 articles.

1. The epidemiology of soft tissue sarcoma;Zahm;Semin Oncol,1997

2. Epidemiology of bone and soft tissue sarcomas;McClay;Semin Oncol,1989

3. Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus;Kanerva;Mol Ther,2003

4. Modified adenoviruses for cancer gene therapy;Kanerva;Int J Cancer,2004

5. Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14;Wang;Nat Med,2011

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