Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2‐Hydroxypropyl‐β‐Cyclodextrin Treatment

Author:

Jarazo Javier12ORCID,Barmpa Kyriaki1ORCID,Modamio Jennifer1ORCID,Saraiva Cláudia1ORCID,Sabaté‐Soler Sònia1ORCID,Rosety Isabel1ORCID,Griesbeck Anne3,Skwirblies Florian3,Zaffaroni Gaia4ORCID,Smits Lisa M.1,Su Jihui5,Arias‐Fuenzalida Jonathan1,Walter Jonas1ORCID,Gomez‐Giro Gemma1ORCID,Monzel Anna S.1ORCID,Qing Xiaobing1,Vitali Armelle6,Cruciani Gerald67,Boussaad Ibrahim67ORCID,Brunelli Francesco8ORCID,Jäger Christian9ORCID,Rakovic Aleksandar10ORCID,Li Wen5,Yuan Lin5,Berger Emanuel1,Arena Giuseppe6ORCID,Bolognin Silvia1ORCID,Schmidt Ronny3,Schröder Christoph3ORCID,Antony Paul M.A.6ORCID,Klein Christine10ORCID,Krüger Rejko61112ORCID,Seibler Philip10,Schwamborn Jens C.1ORCID

Affiliation:

1. Developmental and Cellular Biology Luxembourg Centre for Systems Biomedicine University of Luxembourg Esch‐sur‐Alzette Luxembourg

2. OrganoTherapeutics société à responsabilité limitée simplifiée (SARL‐S) Esch‐sur‐Alzette Luxembourg

3. Sciomics GmbH Heidelberg Germany

4. Institute for Globally Distributed Open Research and Education Gothenburg Sweden

5. Institute of Health Sciences China Medical University Shenyang China

6. Translational Neuroscience, Luxembourg Centre for Systems Biomedicine University of Luxembourg Esch‐sur‐Alzette Luxembourg

7. Disease Modeling and Screening Platform Luxembourg Institute of Systems Biomedicine, University of Luxembourg and Luxembourg Institute of Health Belvaux Luxembourg

8. Department of Molecular Medicine University of Pavia Pavia Italy

9. Metabolomics Platform, Enzymology and Metabolism Luxembourg Centre for Systems Biomedicine University of Luxembourg Esch‐sur‐Alzette Luxembourg

10. Institute of Neurogenetics University of Lübeck Lübeck Germany

11. Centre Hospitalier de Luxembourg Parkinson Research Clinic Luxembourg Luxembourg

12. Transversal Translational Medicine Luxembourg Institute of Health Strassen Luxembourg

Funder

Deutsche Forschungsgemeinschaft

Fonds National de la Recherche Luxembourg

Horizon 2020 Framework Programme

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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