Drug-induced liver injury: Advances in mechanistic understanding that will inform risk management

Author:

Mosedale M1,Watkins PB1

Affiliation:

1. Institute for Drug Safety Sciences, University of North Carolina at Chapel Hill, Research Triangle Park, North Carolina, USA; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy; Chapel Hill North Carolina USA

Funder

National Institute of Diabetes and Digestive and Kidney Diseases Project

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference74 articles.

1. Drug-induced acute liver failure;Lee;Clin Liver Dis.,2013

2. Idiosyncratic drug-induced liver injury is associated with substantial morbidity and mortality within 6 months from onset;Fontana;Gastroenterology,2014

3. How to diagnose and exclude drug-induced liver injury;Watkins;Dig Dis (Basel).,2015

4. Drug safety sciences and the bottleneck in drug development;Watkins;Clin Pharmacol Ther.,2011

5. http://www.bloomberg.com/news/2013-12-27/takeda-scraps-development-of-diabetes-drug-on-risks-shares-drop.html Takeda Shares Drop After Scrapping Development of Diabetes Drug 2013

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