Understanding the effect of high gas entrance velocity on Chinese hamster ovary (CHO) cell culture performance and its implications on bioreactor scale‐up and sparger design-Reference-Cited by-同舟云学术

Understanding the effect of high gas entrance velocity on Chinese hamster ovary (CHO) cell culture performance and its implications on bioreactor scale‐up and sparger design

Published:2020-02-28 Issue:6 Volume:117 Page:1684-1695
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Chaudhary Garima¹,Luo Robin¹,George Meena¹,Tescione Lia¹,Khetan Anurag¹,Lin Henry¹^ORCID

Affiliation:

1. Cell Culture, Process ScienceBoehringer Ingelheim Fremont, Inc. 6701 Kaiser Drive Fremont California

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27314

Reference23 articles.

1. Death mechanisms of animal cells in conditions of intensive agitation

2. Hydrodynamic stress and lethal events in sparged microalgae cultures

3. Overcoming shear stress of microalgae cultures in sparged photobioreactors

4. Mixing, aeration and cell damage, 30+ years later: what we learned, how it affected the cell culture industry and what we would like to know more about

5. Animal-cell damage in sparged bioreactors

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