Affiliation:
1. Department of Hematology Faculty of Medicine, Al Assad University Hospital Damascus Syria
2. Department of Hematology Faculty of Medicine, Al‐Mouwasat University Hospital Damascus Syria
Abstract
Key Clinical MessageDown syndrome (DS), characterized by trisomy 21, significantly increases susceptibility to leukemia, although the occurrence of multiple myeloma (MM) in DS is exceedingly rare. This report details the case of a 45‐year‐old female with DS who was diagnosed with MM, highlighting diagnostic and therapeutic complexities. It emphasizes the importance of tailored therapeutic strategies for treating MM in individuals with DS and the need for specialized approaches in these cases.