CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence

Author:

Colombo Chiara1,Miceli Rosalba2,Lazar Alexander J.34,Perrone Federica5,Pollock Raphael E.46,Le Cesne Axel7,Hartgrink Henk H.8,Cleton-Jansen Anne-Marie9,Domont Julien7,Bovée Judith V. M. G.9,Bonvalot Sylvie10,Lev Dina411,Gronchi Alessandro1

Affiliation:

1. Sarcoma Service; Department of Surgery; Scientific Institute for Research; Hospitalization; and Health Care (IRCCS) Foundation; National Cancer Institute; Milan Italy

2. Unit of Clinical Epidemiology and Trial Organization; IRCCS Foundation; National Cancer Institute; Milan Italy

3. Department of Pathology; The University of Texas MD Anderson Cancer Center; Houston Texas

4. The Sarcoma Research Center; The University of Texas MD Anderson Cancer Center; Houston Texas

5. Department of Pathology; IRCCS Foundation; National Cancer Institute; Milan Italy

6. Department of Surgical Oncology; The University of Texas MD Anderson Cancer Center; Houston Texas

7. Department of Medical Oncology; Gustave Roussy Institute; Villejuif France

8. Department of Surgery; Leiden University Medical Center; Leiden The Netherlands

9. Department of Pathology; Leiden University Medical Center; Leiden The Netherlands

10. Department of Surgery; Gustave Roussy Institute; Villejuif France

11. Department of Cancer Biology; The University of Texas MD Anderson Cancer Center; Houston Texas

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference18 articles.

1. Aggressive fibromatosis of the abdominal wall, limbs and limb girdles;Phillips;Br J Surg.,2004

2. Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution;Gronchi;J Clin Oncol.,2003

3. Optimizing treatment of desmoid tumors;Lev;J Clin Oncol.,2007

4. Increased Beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors);Alman;Am J Pathol.,1997

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