Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors-Reference-Cited by-同舟云学术

Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors

Published:2018-07-30 Issue:9 Volume:48 Page:1573-1579
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Alexander Tobias¹²^ORCID,Cheng Qingyu¹²^ORCID,Klotsche Jens³,Khodadadi Laleh¹²,Waka Aderajew¹²,Biesen Robert¹²,Hoyer Bimba F.¹²⁴,Burmester Gerd R.¹,Radbruch Andreas⁵^ORCID,Hiepe Falk¹²^ORCID

Affiliation:

1. Department of Rheumatology and Clinical Immunology; Charité-University Medicine Berlin; Germany

2. German Rheumatism Research Center (DRFZ); a Leibniz Institute, Autoimmunology Group; Berlin Germany

3. German Rheumatism Research Center (DRFZ); a Leibniz Institute, Epidemiology Group; Berlin Germany

4. Medical Clinic I; University Hospital Schleswig-Holstein; Campus Kiel Germany

5. German Rheumatism Research Center (DRFZ); a Leibniz Institute, Cell Biology Group; Berlin Germany

Funder

Innovative Medicines Initiative 2 Joint undertaking

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201847492/fullpdf

Reference24 articles.

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2. Autoantibodies from long-lived ‘memory’ plasma cells of NZB/W mice drive immune complex nephritis;Cheng;Ann. Rheum. Dis.,2013

3. Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice;Hoyer;J. Exp. Med.,2004

4. Bone marrow of NZB/W mice is the major site for plasma cells resistant to dexamethasone and cyclophosphamide: implications for the treatment of autoimmunity;Mumtaz;J. Autoimmun.,2012

5. Plasma cells as an innovative target in autoimmune disease with renal manifestations;Hiepe;Nat. Rev. Nephrol.,2016

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