Experimental design for the optimization and robustness testing of a liquid chromatography tandem mass spectrometry method for the trace analysis of the potentially genotoxic 1,3-diisopropylurea-Reference-Cited by-同舟云学术

Experimental design for the optimization and robustness testing of a liquid chromatography tandem mass spectrometry method for the trace analysis of the potentially genotoxic 1,3-diisopropylurea

Published:2013-11-15 Issue:9 Volume:6 Page:898-908
ISSN:1942-7603
Container-title:Drug Testing and Analysis
language:en
Short-container-title:Drug Test. Analysis

Author:

Székely György¹²,Henriques Bruno¹,Gil Marco¹,Alvarez Carlos¹

Affiliation:

1. Hovione PharmaScience; Lisbon 2674 - 506 Portugal

2. Department of Chemical Engineering; Imperial College London, Exhibition Road; London SW7 2AZ UK

Funder

European Commission

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference44 articles.

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4. Organic solvent nanofiltration: A platform for removal of genotoxins from active pharmaceutical ingredients;Székely;J. Membr. Sci.,2011

5. Removal of electrophilic potential genotoxic impurities using nucleophilic reactive resins;Lee;Org. Process Res. Dev.,2010

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