SARS‐CoV‐2 in patient with protein C deficiency: A case report

Author:

Ahmadi Akram Sadat1ORCID,Shafiei‐Jandaghi Nazanin Zahra1ORCID,Sadeghi Kaveh1ORCID,Salimi Vahid1ORCID,Nejati Ahmad1ORCID,Azad Talat Mokhtari1ORCID,Yavarian Jila12ORCID

Affiliation:

1. Department of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran

2. Research Center for Antibiotic Stewardship and Antimicrobial Resistance Tehran University of Medical Sciences Tehran Iran

Abstract

Key clinical messageIn SARS‐CoV‐2 pandemic different disorders in coagulation pathways in COVID‐19 patients were reported. We described a 44‐year‐old female with COVID‐19 and protein C deficiency history. She did not show any coagulation disorder during her disease course. Complete genome sequencing of SARS‐CoV‐2 was performed and some mutations identified and compared with Wuhan strain. Besides hospitalized patients, in COVID‐19 outpatients with low concentration of protein C, early prescription of an anticoagulant such as heparin could be helpful in prevention of venous thromboembolism or pulmonary embolism.

Publisher

Wiley

Subject

General Medicine

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