Hepcidin-dependent and hepcidin-independent regulation of erythropoiesis in a mouse model of anemia of chronic inflammation

Author:

Langdon Jacqueline M.1,Yates Saiah C.1,Femnou Laurette K.1,McCranor Bryan J.1,Cheadle Chris2,Xue Qian-Li13,Vaulont Sophie4,Civin Curt I.56,Walston Jeremy D.1,Roy Cindy N.17

Affiliation:

1. Division of Geriatric Medicine and Gerontology; Johns Hopkins University School of Medicine; Baltimore Maryland

2. Lowe Family Genomics Core; Johns Hopkins University School of Medicine; Baltimore Maryland

3. Department of Epidemiology; Johns Hopkins Bloomberg School of Public Health; Baltimore Maryland

4. Institut Cochin, Institut National de la Santé et de la Recherche Medicale U1016; Paris France

5. Center for Stem Cell Biology and Regenerative Medicine; Department of Pediatrics; University of Maryland; Baltimore Maryland

6. Center for Stem Cell Biology and Regenerative Medicine; Department of Physiology; University of Maryland; Baltimore Maryland

7. Division of Hematology; Johns Hopkins University School of Medicine; Baltimore Maryland

Funder

American Society of Hematology Minority Medical Student Award Program

Publisher

Wiley

Subject

Hematology

Reference53 articles.

1. Anemia WSGoID Iron Deficiency Anemia Report of a Study group. Switzerland: World Health Organization technical report series 1959

2. The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders;Ganz;Hematology/the Education Program of the American Society of Hematology American Society of Hematology,2011

3. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation;Nicolas;J Clin Invest,2002

4. Lee P Peng H Gelbart T Regulation of hepcidin transcription by interleukin-1 and interleukin-6 Proc Natl Acad Sci USA 2005 102 1906 1910

5. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin;Nemeth;J Clin Invest,2004

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