Protein expression of various hepatic uridine 5′-diphosphate glucuronosyltransferase (UGT) enzymes and their inter-correlations: a meta-analysis-Reference-Cited by-同舟云学术

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Protein expression of various hepatic uridine 5′-diphosphate glucuronosyltransferase (UGT) enzymes and their inter-correlations: a meta-analysis

Published:2014-08-06 Issue:6 Volume:35 Page:353-361
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Achour Brahim¹,Rostami-Hodjegan Amin¹²,Barber Jill¹

Affiliation:

1. Manchester Pharmacy School; University of Manchester; Manchester UK

2. Simcyp Limited (a Certara Company); Sheffield UK

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference35 articles.

1. Intestinal UGTs as potential modifiers of pharmacokinetics and biological responses to drugs and xenobiotics;Ritter;Expert Opin Drug Metab Toxicol,2007

2. Predicting in vivo drug interactions from in vitro drug discovery data;Wienkers;Nat Rev Drug Discov,2005

3. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors;Walsky;Drug Metab Dispos,2012

4. The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drug-drug interaction potential;Miners;Drug Metab Rev,2010

5. Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver;Barter;Curr Drug Metab,2007

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