Affiliation:
1. General Surgery Department Guilan University of Medical Sciences Rasht Iran
2. Burn and Regenerative Medicine Research Center Guilan University of Medical Sciences Rasht Iran
3. Department of Statistics, Faculty of Mathematical Sciences University of Guilan Rasht Iran
4. Clinical Research Development Unit of Poursina Hospital Guilan University of Medical Sciences Rasht Iran
5. School of Medicine, Razi Hospital Guilan University of Medical Sciences Rasht Iran
Abstract
AbstractBackground and AimsDiabetic foot ulcers (DFU) are a severe complication in diabetes patients, often resulting in significant morbidity and mortality due to non‐healing. This study investigated the effectiveness of 5% topical potassium permanganate on these ulcers.MethodsA clinical trial was conducted on 23 patients with Wagner grade I and II DFU. Patients in the control group received standard treatment, while those in the intervention group also received 5% potassium permanganate topically. Data were recorded at 0, 7, 14, and 21 days for analysis.ResultsAmong 23 patients studied, 7 (30.4%) were male and 16 (43.7%) female, with an average age of 59 ± 4 years. Both groups showed a statistically significant decrease in wound size and infection over time (p < 0.001). The intervention group, however, had a more substantial reduction in wound size and infection rate (p < 0.05).ConclusionPotassium permanganate, when applied topically, is both well‐tolerated and effective in enhancing wound healing and reducing infection in DFU, suggesting its potential as a complementary treatment.