A novel DNA intercalator, 8-methoxy pyrimido[4′,5′:4,5]thieno (2,3-b)quinoline-4(3H)-one induces apoptosis in cancer cells, inhibits the tumor progression and enhances lifespan in mice with tumor

Author:

Sharma Sheetal,Panjamurthy Kuppusamy,Choudhary Bibha,Srivastava Mrinal,Shahabuddin MS,Giri Ranjit,Advirao Gopal M.,Raghavan Sathees C.

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

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3. Sandramycin, a novel antitumor antibiotic produced by a Nocardioides sp. Production, isolation, characterization and biological properties;Matson;J Antibiot (Tokyo),1989

4. Synthesis of key sandramycin analogs: Systematic examination of the intercalation chromophore;Boger;Bioorg Med Chem,1998

5. Biological properties of 8-methoxypyrimido[4(1),5(1):4,5]thieno(2,3-b)quinoline-4(3H)-one, a new class of DNA intercalating drugs;Gopal;Indian J Med Res,2004

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