Low‐Dose Interleukin‐2 for Refractory Autoimmune Hepatitis
Author:
Affiliation:
1. Institute of Liver Studies, King’s College Hospital, Medical Research Council Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and MedicineKing’s College London London UK
Funder
King's Health Partners
Medical Research Council
European Association for the Study of the Liver
Publisher
Wiley
Subject
Hepatology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep.30059
Reference4 articles.
1. Low-Dose Interleukin-2 Therapy Restores Regulatory T Cell Homeostasis in Patients with Chronic Graft-Versus-Host Disease
2. Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial
3. In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression
4. Liver inflammation abrogates immunological tolerance induced by Kupffer cells
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