Small Molecule Microarray Based Discovery of PARP14 Inhibitors
Author:
Affiliation:
1. Department of Chemistry National University of Singapore 3 Science Drive Singapore 117543 Singapore
2. Karolinska Institute Department of Medical Biochemistry & Biophysics Scheeles väg 2 17177 Stockholm Sweden
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.201609655
Reference34 articles.
1. New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
2. The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
3. Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
4. Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma
5. PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation
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