Eine DNA‐kodierte Molekülbibliothek mit Elementen natürlicher Makrocyclen
Author:
Affiliation:
1. Department ChemieUniversität Basel St. Johanns-Ring 19 4056 Basel Schweiz
2. Biophysikalisches InstitutBiozentrumUniversität Basel Klingelbergstrasse 50/70 4056 Basel Schweiz
Funder
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.201902513
Reference59 articles.
1. The exploration of macrocycles for drug discovery — an underexploited structural class
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3. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
4. Drug-like properties and the causes of poor solubility and poor permeability
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